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10 Jan 2013

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Forest Pathology technician, Roslin, Edinburgh

A vacancy exists for a Forest Pathology technician with Forest Research based in Roslin, Edinburgh. This is a full-time, permanent position. Closing date for applications 15th January. More details can be obtained from the Forestry Commission website, or by following the direct link provided here.

PhD studentship in molecular plant pathology (deadline 31 Jan 2013)
Royal Holloway, University of London (RHUL)
(DTP program, BBSRC funded for UK citizens and EU citizen meeting UK residency qualifications)

RNAi to silence fungal effectors in barley for disease control of powdery mildew
Effector proteins are secreted by pathogenic fungi into the plant host that is being invaded. Effectors are compromising the host immune response, therefore silencing of effectors might be a strategy for controlling plant diseases. HIGS (Host induced gene silencing) is suitable to validate effector functions of the fungal pathogen barley powdery mildew (Blumeria graminis f.sp. hordei, Bgh), but only a small proportion of cells transiently express siRNAs, thus HIGS is not applicable for disease control, or high-throughput screening of 450+ putative Bgh effectors (Spanu et al, 2010). Therefore we will use novel approaches to improve the direct uptake of small synthetic interfering nucleotides to silence Bgh effectors. We will use such technology to silence and validate Bgh (putative) effectors. This will be further exploited as a new strategy for crop disease control of economically important biotrophs such as cereal powdery mildews and wheat rusts. This approach will also be exploited to challenge host proteins for their role in Bgh resistance/ susceptibility.

Application information and forms can be found on Applications (form, CV and references) must be emailed to Mrs Tracey Jeffries: before 31 January 2013.
Supervisor and informal enquiries:  Dr L. Bindschedler, RHUL: ;
Co-supervisor:: Dr C. Turnbull, Imperial College