|This part-time role will assist authors globally in the curation of literature using a newly developed web-based community curation tool called PHI-Canto, canto.phi-base.org. The literature curated will pertain to a wide range of functional genomics and functional genetics studies that will have been recently published by authors through the peer review process. The focus of this assisted curation is the published peer-reviewed literature on molecular host-pathogen interactions, and in particular, single/multiple gene deletion studies in pathogenic fungi, bacteria and protists, as well as effector characterisation studies and articles reporting on the first host targets of pathogen effectors in natural and/or non-host model species. The pathogen species to be curated cause diseases in plant, human, animal, insect and/or other hosts.
The post-holder will join the long established four-person Pathogen-Host Interaction database (PHI-base) team based at Rothamsted Research. PHI-base, www.phi-base.org, is a gold-standard manually curated phenotype database storing molecular information on genes implicated in virulence (Urban et al., Nucleic Acids Research, database issue 2020 and 2022). Our September 2021 PHI-base release (version 4.12) provides information on 279 pathogens tested on 228 hosts, and contains information from > 4,300 articles and > 18,000 interactions. Species-neutral high-level phenotypes are used to describe the overall pathogen-host interaction outcomes using the newly developed Pathogen-Host Interaction Phenotype Ontology (PHIPO) registered at the OBO Foundry. PHI-base is a FAIR database and its data and ontology terms are disseminated to Ensembl Genomes, UniProtKB, FungiDB and the KnetMiner knowledge graph tool. PHI-base is a member of the UK node of the ELIXIR ‘Data for Life’ project.
Besides assisting with the author curation and expert checking process, the post-holder will be expected to spend time assisting with reports to funders and the project scientific advisory board, research manuscripts, and presenting their work both internally to colleagues and sometimes externally at scientific conferences/workshops.
The post-holder will actively interact by email and online meetings with other project partners, principally the curation company Molecular Connections (based in India) which is also using the PHI-Canto curation tool as well as the ENSEMBL Invertebrates team and the PomBase team, both based in Cambridge (UK). The post-holder will also interact with external collaborators, mainly journal editors, principally New Phytologist in the first instance.
This 20% post (1 day a week) will start in February 2022 and will run until 30th June 2022, in the first instance. This post could be extended until autumn 2022 based on the post holder’s performance. There is also the possibility of an extension for a further 3 years if additional BBSRC-BBR funding is secured (application already submitted). To ensure the post holder is completely trained and fully familiar with the PHI-Canto tool and the associated procedures when engaging with authors, during weeks 1 through 8, some additional hours (3.7 – 7.4 per week) will be required. Further details and requirements can be found in the job description and person specification.
This fixed term, part-time position offers a salary in the range of £29,842-32,315 p.a. (pro-rata)
Informal enquiries can be directed to firstname.lastname@example.org